In Vitro Cell Culture of Rhus coriaria L.: A Standardized Phytocomplex Rich of Gallic Acid Derivatives with Antioxidant and Skin Repair Activity

This study focused on the biological evaluation and chemical characterization of a new ingredient obtained by in vitro cell culture Rhus coriaria L. An plant method permits to cultivate short period time obtain extract with high safety profile for consumer, free from heavy metals, pesticides, aflatoxins, bacterial or fungal contamination. Through selection specific media, it was possible line content gallic acid derivatives. The phytocomplex (RC-P), containing 7.6% w/w derivatives, drying biomass after 14 days growth final selected medium. UPLC-ESI-MS UPLC-DAD analysis allowed identify numerous such as galloyl hexose, trigalloyl hexose molecular weight quantify their overall content. antioxidant activity RC-P tested DPPH assay wound healing evaluated using scratch test human keratinocytes fibroblasts. work showed that could be effective cosmetic skin repair activity.